Colonel General Adnan Khairallah (Arabic: عدنان خير الله طلفاح, romanized: ʿAdnān Khayr Allāḥ; 1940 – 4 May 1989) was an Iraqi military officer and Saddam Hussein's brother in-law and cousin. He held several titles and was a member of the Iraqi Revolutionary Command Council. He also served as the Defence Minister of Iraq from 1979 until his death a decade later, being appointed days after Saddam Hussein succeeded to the Presidency.

He died in 1989 in a helicopter crash that was officially labeled an accident. The circumstances surrounding his death, including his disputes with Saddam and rumors of a potential coup, have led some to believe Adnan was assassinated under orders from Saddam.