William Frederick Burr (born June 10, 1968) is an American stand-up comedian, podcaster, actor, writer, and director. He started his career as a stand-up comedian before expanding his career as an actor on stage and screen. As a comedian he is known for his sharp confrontational observational humor often tackling subjects such as social issues, politics and the absurdities of the human condition. He has received nominations for a Emmy Award and a Grammy Award. In 2017, Rolling Stone ranked him 17th on its list of the "50 Best Stand-Up Comics of All Time".

Burr's most notable stand-up comedy specials include You People Are All the Same (2012), I'm Sorry You Feel That Way (2014), Walk Your Way Out (2017), and Paper Tiger (2019). He has also hosted the Monday Morning Podcast every Monday and Thursday since 2007, and co-founded the All Things Comedy network in 2012. He received a Grammy Award for Best Comedy Album nomination for Paper Tiger and a Primetime Emmy Award for Outstanding Actor in a Short Form Comedy or Drama Series nomination for the Quibi series Immoral Compass (2021).

Burr created, co-wrote, and voiced the lead character in the Netflix animated sitcom F Is for Family (2015–2021). His other notable roles include various characters in Chappelle's Show (2004), Patrick Kuby in the AMC crime drama series Breaking Bad (2011–2013), Migs Mayfeld in The Mandalorian (2019–present), and John F. Kennedy in the film Unfrosted (2024). He made his feature-length directorial debut as the co-writer, director, and star of the comedy film Old Dads (2023) and has had supporting roles in Daddy's Home (2015), Daddy's Home 2 (2017), and The King of Staten Island (2020). He made his Broadway debut in the 2025 revival of the David Mamet play Glengarry Glen Ross.