The Boötes Void ( boh-OH-teez) (colloquially referred to as the Great Nothing) is a roughly spherical region of space in the vicinity of the constellation Boötes. It contains just 60 galaxies, which is significantly lower than the approximately 2,000 galaxies expected for an area of comparable size. With a radius of 62 megaparsecs (nearly 330 million light-years), it is one of the largest known voids in the visible universe, and is often referred to as a "supervoid".

It was discovered in 1981 by astronomer Robert Kirshner as part of a survey of galactic redshift. Its centre is located 700 million light-years from Earth, at right ascension 14^h 50^m and declination 46°.

The Hercules Superclusters are part of the near edge of the void.