Maura Murray (born May 4, 1982) is an American woman who disappeared on the evening of February 9, 2004, after a car crash on Route 112 near Woodsville, New Hampshire, a village in the town of Haverhill. Her whereabouts remain unknown. Murray was a 21-year-old nursing student completing her junior year at the University of Massachusetts Amherst (UMass Amherst) at the time of her disappearance.

On the afternoon of Monday, February 9, before she left the UMass Amherst campus, Murray emailed her professors and work supervisor, writing that she was taking a week off due to a death in the family; according to her family, no such death had taken place. At 7:27 pm, a local woman reported a car accident on a sharp corner of Route 112 adjacent to her home. A passing motorist who also lived nearby stopped at the scene and asked the woman driving the car if she needed assistance; she declined, claiming to have called roadside assistance. Upon arriving home several minutes later, the motorist reported the accident to emergency services. At 7:46 pm, law enforcement arrived at the scene, but the woman had disappeared.

Police traced the vehicle to Murray, and initially treated her as a missing person on the belief that she may have wanted to disappear voluntarily. This speculation was based on her travel preparations (about which she had confided nothing to friends or family) and no obvious evidence of foul play. In 2009, Murray's case was given to New Hampshire's cold case division, and authorities are handling it as a "suspicious" missing persons case.

In the years after Murray's disappearance, her case would receive media attention on TV programs such as 20/20 and Disappeared, and also garner significant speculation on Internet message boards and forums, with theories ranging from abduction to voluntary disappearance. In 2017 the case was the subject of a documentary series on the Oxygen network, which described Murray's disappearance as the "first crime mystery of the social media age," having occurred days after the launch of Facebook.