John Edmund Mulaney (born August 26, 1982) is an American stand-up comedian, actor, writer, and producer. Born and raised in Chicago, Illinois, Mulaney first rose to prominence for his work as a writer for the NBC sketch comedy series Saturday Night Live from 2008 to 2013, where he contributed to numerous sketches and characters, including Stefon, a recurring character that he and Bill Hader co-created. Since his departure from SNL, Mulaney has hosted it six times, becoming a member of the SNL Five Timers Club in 2022.

Mulaney's stand-up specials include The Top Part (2009), New in Town (2012), The Comeback Kid (2015), Kid Gorgeous (2018), and Baby J (2023). He won two Primetime Emmy Awards for Outstanding Writing for a Variety Special for Kid Gorgeous and Baby J. Mulaney released a children's musical comedy special on Netflix, John Mulaney & the Sack Lunch Bunch (2019).

He was the creator and star of the short-lived semi-autobiographical Fox sitcom Mulaney (2014–2015). Mulaney also performs George St. Geegland in a comedic duo with Nick Kroll, and they appeared on television and on Broadway in the show Oh, Hello on Broadway (2016–2017). Mulaney serves as a co-executive producer, writer, and occasional actor in the IFC mockumentary series Documentary Now! (2015–present). He hosted, created, and executive produced the Netflix talk show John Mulaney Presents: Everybody's in LA (2024).

Mulaney's voice roles include Andrew Glouberman in the Netflix original animated show Big Mouth (2017–present), Peter Porker / Spider-Ham in Spider-Man: Into the Spider-Verse (2018), Chip in Chip 'n Dale: Rescue Rangers, and Big Jack Horner in Puss in Boots: The Last Wish (2022).