Jose Rodolfo Villarreal-Hernandez (born January 16, 1978) is a Mexican drug cartel boss and former fugitive who was added to the FBI Ten Most Wanted Fugitives list on October 13, 2020. He was wanted for orchestrating the murder of Juan Jesús Guerrero Chapa, which was carried out on May 22, 2013, in Southlake, Texas. He is also believed to be responsible for numerous murders in Mexico. Villarreal-Hernandez was the 524th fugitive to be placed on the FBI's Ten Most Wanted Fugitives list. He replaced Santiago Villalba Mederos. The United States Department of State's Transnational Organized Crime Rewards Program offered a reward of up to $1 million for information leading directly to his arrest. He was captured on January 7, 2023. On February 27, 2025, he was extradited to the United States.