Below is a list of Major League Baseball no-hitters, enumerating every no-hitter pitched in Major League Baseball history. The list also includes no-hit games that were broken up in extra innings or were in shortened games, although they have not been considered official no-hitters since 1991.

Through September 4, 2024, there have been 326 no-hitters recognized by Major League Baseball (MLB): 43 before the formation of the American League in 1901, and the rest in the modern era. Three other games are also noted: one in 1875 by Joe Borden that is accepted as a no-hitter in the National Association but not as a major league game, one in 1876 by Borden that is disputed and not recognized by MLB, and one in 1901 by Pete Dowling that is also disputed and not recognized by MLB. The first no-hitter officially recognized by MLB was pitched by George Bradley on July 15, 1876, during the first season of play in the National League. The most recent major league no-hitter was thrown by Chicago Cubs pitchers Shota Imanaga, Nate Pearson, and Porter Hodge against the Pittsburgh Pirates on September 4, 2024.