Melissa Ann McCarthy (born August 26, 1970) is an American actress, comedian, screenwriter, and producer. She is the recipient of numerous accolades, including two Primetime Emmy Awards, and nominations for two Academy Awards and two Golden Globe Awards. McCarthy was named by Time as one of the 100 most influential people in the world in 2016, and she has been featured multiple times in annual rankings of the highest-paid actresses in the world. In 2020, The New York Times ranked her #22 in its list of the 25 Greatest Actors of the 21st Century.

McCarthy has received two Primetime Emmy Awards, her first for Outstanding Lead Actress in a Comedy Series for playing Molly Flynn on the CBS sitcom Mike & Molly (2010–2016) followed by her win for Outstanding Guest Actress in a Comedy Series for hosting Saturday Night Live (2017). She has also taken recurring roles in the comedy-drama series Gilmore Girls (2000–2007) and the sitcom Samantha Who? (2007–2009), a leading role in the miniseries Nine Perfect Strangers (2021), and a guest role in the comedy series Only Murders in the Building (2024).

On film, she has received two Academy Award nominations for Best Supporting Actress playing a comedic bridesmaid in the comedy Bridesmaids (2011) and Best Actress for her portrayal of writer Lee Israel in the biographical film Can You Ever Forgive Me? (2018). She has also starred in a string of commercially successful comedies such as Identity Thief (2013), The Heat (2013), Tammy (2014), St. Vincent (2014), Spy (2015), The Boss (2016), and Life of the Party (2018). She played Ursula in the musical fantasy film The Little Mermaid (2023).

McCarthy and her husband Ben Falcone are the founders of the production company On the Day Productions, under which they have collaborated on several comedy films including Super Intelligence (2020), and Thunder Force (2021). In 2015, she launched her own clothing line for plus-sized women, named Melissa McCarthy Seven7, and she received a motion picture star on the Hollywood Walk of Fame.