On the Case with Paula Zahn is an American documentary and news program broadcast on Investigation Discovery since October 18, 2009. The program explores in-depth stories of crime mysteries and interviews with involved individuals, closest to the cases and includes expert analysis. Emmy Award winning journalist and former CNN anchor Paula Zahn is the program host who travels throughout the country interviewing people directly affected by the tragic cases.

On the Case with Paula Zahn is the first series on Investigation Discovery to reach over 360 episodes.