Hamzah bin Al Hussein (Arabic: حمزة بن الحسين; born 29 March 1980) is the fourth son of King Hussein bin Talal of Jordan overall and the first by his American-born fourth wife, Queen Noor. He was named Crown Prince of Jordan on 7 February 1999, a position he held until his older half-brother, King Abdullah II, rescinded it on 28 November 2004. He is a member of the Hashemite dynasty, the royal family of Jordan since 1921, and is a 41st-generation direct descendant of Muhammad.

Hamzah is reputed to be under house arrest since April 2021, after being accused of attempting to destabilise the Kingdom of Jordan and fomenting unrest. Hamzah officially renounced his title as prince in April 2022.