Santhanam Neelamegam (born 21 January 1980) is an Indian actor and film producer who mainly works in Tamil cinema. Beginning his career as a comedian on television, he rose to fame through his performances in Star Vijay's Lollu Sabha enacting the lead role in spoofs of Tamil films. He was subsequently given a chance by actor Silambarasan to feature in a supporting role in Manmadhan (2004) and then was signed on to appear in a host of films, notably winning good reviews for his work in Sachein (2005) and Polladhavan (2007). He appeared in a one-off leading role in Shankar's production Arai En 305-il Kadavul (2008) and became a staple feature as a comedian with his brand of insult comedy becoming very successful during the period, with his market popularity helping stuck films find distributors.

Santhanam has also had embarked on collaborations with directors including gaining positive reviews for his work in M. Rajesh's comic trilogy of Siva Manasula Sakthi (2009), Boss Engira Bhaskaran (2010) and Oru Kal Oru Kannadi (2012), winning the Vijay Award for Best Comedian for each one. He has also repeatedly collaborated in the films of A. L. Vijay, Siva and Sundar C as well.

His consistently well-received performances and box office appeal in the early 2010s prompted the film industry to dub him as the "Comedy Superstar". In 2012, he began a film production company named Handmade Films and produced his first film, Kanna Laddu Thinna Aasaiya (2013), which went on to become a commercially successful venture. Meanwhile, in 2014, he starred in the leading role for the second time in the action comedy Vallavanukku Pullum Aayudham.