Zipline International Inc. is an American company that designs, manufactures, and operates delivery drones. The company operates distribution centers in the United States, Rwanda, Ghana, Japan, Nigeria, Côte d'Ivoire, and Kenya. As of April 2024, its drones have made more than one million commercial deliveries and flown more than 70 million autonomous miles.

The company designs and manufactures its drones, and builds and operates its distribution centers, which also serve as a drone airport. The company's drones deliver whole blood, platelets, frozen plasma, and cryoprecipitate along with medical products, including vaccines, infusions, and common medical commodities. As of September 2021, more than 75 percent of blood deliveries in Rwanda outside of Kigali use Zipline drones. In April 2019 in Ghana, the company began using drones to deliver vaccines, blood, and medicines. In addition, during the COVID-19 pandemic in 2020, the US Federal Aviation Administration (FAA) granted a Part 107 aviation waiver to Zipline's partner organization Novant Health for the delivery of medical supplies and personal protective equipment (PPE) to medical facilities in North Carolina.

The company also offers delivery services for non-medical products, including partnerships with Walmart which started in 2021, and with Sweetgreen which was announced in 2023. Its website features uses for restaurants, groceries, convenience shopping, and e-commerce.